Olfactory neuroblastoma as acute postpartum depression.

Olfactory neuroblastoma is a rare neuroectodermal malignant tumor. It was first described by Berger et al in 1924, I and about 250 cases have since been reported, none of them in the perinatal period. The tumor emerges from the olfactory membrane located in the sinonasal area and anterior cranial fossa. It has a broad histologic spectrum and can be confused with peripheral neuroectodermal tumors. Z Early symptoms are intranasal obstruction, epistaxis, and anosmia.3 As the tumor grows, it can invade the oral cavity,4 the orbits, and the brain,3,5 In very rare cases the initial symptom is depression and frontal lobe dysfunction.6 We describe a patient with olfactory neuroblastoma in whom the presenting symptom resembled postpartum depression.